I know that there can be sonic and imaging differences between different amplifier designs, even when their frequency responses into the load are identical. The UPA-500 with the LXmini sounds neutral and spatially detailed over the whole frequency range, immediately and in long-term listing. I also have listened to different amplifiers and front ends through the LXmini and find the speakers revealing of sonic differences in equipment. Thus, if you like to play this audiophile game - and often endless search - the LXmini is a speaker that can make it fun and rewarding because it tells you right away if you have come closer or moved away from "reality". Stereo is an illusion, a mental construct of an acoustic scene, which the recording engineer has sampled with n-microphones and processed. The only connection to reality is your accumulated auditory memory of live acoustic events. The 3D rendering, which the LXmini delivers to your ear/brain perceptual apparatus from the cues in a well done recording, can be like a convincing magic show.
The difference in power requirements for woofer vs. mid/tweeter opens the door to Class-A power amplifiers for the higher frequencies, where amplifier differences are usually noticed first. But the voltage gain of such amplifier must be made identical to the woofer amplifier's gain in order to stay within the dynamic range of the mini DSP 2x4. Most likely this requires a pre-amplification stage at the power amplifier input. Also, the amplifier output impedance should be <0.5 ohm, i.e. small compared to the rising voice coil impedance, in order not to affect the frequency response of the speaker.
The LM3886 based amplifiers on the PLUTO pcb board are another option. They actually measure quite a bit better than the Emotiva UPA-500 or MINI X-A100 for low distortion at 1 W and 100 mW levels. I give some guidance on the LXmini Owner Support page on how to adapt existing PLUTO amplifier modules for LXmini use, expecting some electronic know-how from the builder for completing such project.
ATI Power Amplifiers
For many years I have been using ATI power amplifiers. In their product line a pair of AT1202 stereo power amplifiers is well suited to the LXmini. Each speaker would have its own 2x120 W stereo amplifier, which can provide as much peak current or peak voltage as you would ever want for the LXmini drivers.
The AT1202 exhibits very good low power intermodulation distortion performance as seen in the graphs above. It is primarily 3rd order at 1 W in response to equal amplitude input signals at 1 kHz and 5.5 kHz driving an 8 ohm resistor. Harmonic distortion products are always lower amplitude than intermodulation products. Unlike for many Class A/B amplifiers the distortion decreases as power goes down. A 100 mW output level is not unrealistic. Early transistor radios had 50 mW output stages and made quite a bit of noise.
Other Power Amplifiers
A wide range of power amplifiers can be used for the LXmini. The primary requirement is that they all have the same voltage gain, otherwise you need to adjust the gain defined by the LXmini configuration file for the miniDSP 2x4 or 4x10HD. I have heard good things from a trusted source about the Outlaw 7075 7-channel amplifier, which measures similar to the AT6012. Here are examples for which I have some measurements.
The AT528NC, Class D, (Hypex NCore technology), 8x 200W, power amplifiers are essential to my ASP System's perfection. They have extremely low distortion even at low output power levels where much of the music detail is happening. Yet the amplifiers also have enormous output current capability to keep the woofers under full control.
Internals of Outlaw 7075 and Dave Reite's UcD180 based 8-channel DIY power amplifier:
PLUTO amplifiers for LXmini